The following S1PR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S1PR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence.

CD363 (S1PR1) Monoclonal Antibody (SW4GYPP), eFluor 660, eBioscience™ Invitrogen catalog: EDG1 (Endothelial Cell Differentiation Gene 1) (APC)

Sphingosine 1-phosphate receptor 1 (S1PR1) plays a pivotal role in mediating trafficking and migration of immune cells. Previous reports also identify S1PR1 as an important susceptibility gene of asthma and other autoimmune disorders. However, little has been known about the regulatory mechanism of S1PR1 expression. S1PR1 - sphingosine-1-phosphate receptor 1 (human) The protein encoded by the S1PR1 gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the We used an inducible mouse model with a temporally disrupted sphingosine-1-phosphate receptor-1 (S1PR1) gene specifically in endogenous effector T cells. Early after infection, WT and S1PR1(-/-) effector T cells localized exclusively within the paracortex.

S1pr1 gene

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is Sphingosine-1-phosphate receptor 1 (S1PR1) was found as a new target gene of miR-. 155 by in vitro and in vivo studies; its expression was decreased in SLE EDG1 is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1- phosphate. 3 Mar 2020 S1pr1 encodes a G-protein-coupled receptor (S1P1) that binds the bioactive signaling molecule sphingosine-1-phosphate (S1P) and is involved tioning downstream of elevated S1P, which contributes to increased S1P receptor 1 (S1pr1) gene expression in the macrophages of several tissues in SCD mice CD363 (S1PR1) Monoclonal Antibody (SW4GYPP), eFluor 660, eBioscience™ Invitrogen catalog: EDG1 (Endothelial Cell Differentiation Gene 1) (APC) 25 Mar 2014 We created an S1P1 (S1pr1) gene-targeting vector that carried a bicistronic unit consisting of the S1P1-tTA fusion followed by a mouse β-arrestin- 7 Mar 2019 Although sphingosine-1-phosphate receptor 1 (S1P1) has been When S1PR1 gene was ablated in the germ line of mice it resulted in a lethal. 10 Sep 2012 We induced S1pr1 gene deletion specifically in endothelial cells using VE- cadherin (Cdh5) promoter-driven Cre recombinase expression by 18 Mar 2020 S1pr1, the gene that encodes S1P1, is highly expressed in endothelial cells, lymphocytes, neuronal cells, and cardiomyocytes [3-6].

This Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 is validated for use in Western Blotting, IHC for the Entrez Gene Number.

understand the role of AIP in pituitary tumorigenesis, we performed gene expression S1PR1 Sphingosine-1-phosphate receptor 1 –1.210 4.69E–06 GPCR. Genes encoding cuticular proteins are components of the Nimrod gene cluster in The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting 1, chromosome, start, end, summit, enrichment score, q value, region, gene 101705225, 101705118, 119.15104, 4.22383, exon, NM_001400, S1PR1, T cell.

Predicted to localize to cytoplasm and intrinsic component of plasma membrane. Is expressed in several structures, including cardiovascular system; fin bud; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human S1PR1 (sphingosine-1-phosphate receptor 1). Genome Resources. Alliance ; Gene:64617 ; VEGA:OTTDARG00000012039

Sphingosine-1-phosphate receptor 1 (HGNC Symbol) Entrez gene summary. The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. Cancer Gene Therapy (2020) S1PR1 as a Novel Promising Therapeutic Target in Cancer Therapy Narges Rostami, Afshin Nikkhoo, Amir Ajjoolabady, Gholamreza Azizi , Mohammad Phenotype data for mouse gene S1pr1.

S1PR1, CD363, CHEDG1, D1S3362, 1901 (S1PR1) 04071 Sphingolipid signaling pathway 1901 (S1PR1) 09133 Signaling molecules and 25 Jun 2019 For example, S1P is reported to regulate gene expression through modulating HDAC1 and HDAC2 activity (38, 40).
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The S1PR1 gene was mapped to river buffalo chromosome 6 using a radiation hybrid panel (Stafuzza et al., 2007).

S1PR1.
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Functional Associations. S1PR1 has 4,557 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 77 datasets.

Edg1 encodes a G-protein-coupled receptor that binds to sphingosine-1-phosphate with high affinity and high specificity. It is essential for vascular development and integrity, and modulates both lymphocyte development and The gene S1PR1 may have Genomic and Proteomic products available from Sigma-Aldrich.

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Clinical and functional impact of recurrent S1PR1 mutations in mantle cell lymphoma. Genetic correlation between multiple myeloma and chronic lymphocytic

EDG1 is a member of the endothelial differentiation gene family. It is a high affinity G protein-coupled receptor for the bioactive lipid, Sphingosine-1- phosphate. 7 Mar 2019 Although sphingosine-1-phosphate receptor 1 (S1P1) has been When S1PR1 gene was ablated in the germ line of mice it resulted in a lethal. 21 Mar 2017 Both S1PR1 and KLF2 gene expression (mRNA, protein) were significantly increased by simvastatin in vitro and in vivo.